Statewide study offers insight into COVID-19 among Hoosiers

Indiana results included in CDC report
Coronavirus Indiana.JPG
Posted at 9:16 PM, Jul 21, 2020
and last updated 2020-07-21 21:16:08-04

INDIANAPOLIS — New data from the Indiana University Fairbanks School of Public Health gives us a better idea what percentage of the population may have COVID-19 or test positive for antibodies.

In Indiana, the figure is 2.8%. Those are the results of the first random sample study in the United States to measure the spread of the virus. The findings were sent to the Centers for Disease Control which included them in its weekly report.

Between April 25 and May 1, researchers tested more than 4,600 Hoosiers for viral infections and antibodies of SARS-CoV-2, the novel coronavirus that causes COVID-19. This number includes more than 3,600 people who were randomly selected from a master list of Indiana residents, and an additional 900 volunteers recruited through nonrandom outreach to the African American and Hispanic communities to get a more in-depth view of the virus's activity within hard-hit populations.

The researchers determined that 1.7 percent of participants tested positive for the novel coronavirus and an additional 1.1 percent tested positive for antibodies, resulting in an estimated overall population prevalence of SARS-CoV-2 of 2.8 percent.

"Because we cannot test everyone, random sample testing allows us to confidently evaluate the spread of COVID-19 in Indiana," said Nir Menachemi, lead scientist on the study and professor and Fairbanks Endowed Chair in the Fairbanks School of Public Health. "The results of this study have furthered our scientific knowledge of COVID-19 and contributed valuable information that influenced complex statewide decision-making."

Participants who reported living with someone who tested positive for COVID-19 had a prevalence rate of 33.6 percent. "The percentage of participants who had a positive test result was 15 times higher among participants who lived with someone who had received a diagnosis of COVID-19," Menachemi said.

"Coupled with the low statewide prevalence, we believe that social distancing efforts helped to minimize the spread of COVID-19 and is an important measure in preventing transmission."

The research team also found that 44.2 percent of participants who tested positive reported no symptoms during the two weeks before testing. Of those who tested positive, 60.3 percent of males reported being asymptomatic, compared to 24.5 of females who were asymptomatic.

“The study’s findings among asymptomatic individuals are crucial to our efforts to mitigate the spread of COVID-19 in Indiana,” said State Health Commissioner Kris Box, M.D., FACOG. “Hoosiers may not feel sick but can still infect someone else, so it’s vital that every Hoosier takes steps to reduce the spread of this virus.”

Rates of current or previous infection were significantly higher among Hispanic participants, at 8.32 percent, than among non-Hispanics, at 2.29 percent.

"Because most Hoosiers had not been infected at the time of the study, we need to continue social distancing, make sure we are washing our hands often and always wearing a mask when we are in public," Menachemi said.