Indianapolis News and Headlines


New study: DNA 'armor gap' may trigger cancer

Posted at 7:06 PM, Feb 02, 2016
and last updated 2016-02-02 19:06:02-05

BLOOMINGTON -- Researchers at Indiana University in Bloomington say they have identified a genetic mechanism that's likely to trigger mutations that can lead to cancer.

The study focuses on an enzyme which is a known trigger for mutations that occur as benign tumor cells transform into cancerous malignancies that spread throughout the body.

The enzyme appears to cause changes by mutating genes during the replication of DNA.

Researchers say the study results could have implications for personalized medicine, which tailors treatments and therapies based upon individual genetic information.


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