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Migraines to cluster headaches: The most painful headaches you could ever have

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Imagine waking up with a slight headache and finding that it lasts for decades.

Or driving to work one day and instead of seeing traffic ahead, you see wavy lines, flashing lights and stars where the cars should be.

An even harsher reality for some is developing a headache that is so excruciating, they start banging their head against a wall, simply to provide some form of relief.

 

 

These are all real -- and harrowing -- forms of headaches felt by many people around the world, where the occurrence is much more than a bout of pain soon fixed with a painkiller.

Instead, these headaches can become a stressful, disabling health problem, and they come in more than 150 forms, from the unusual, like the "alarm clock" headache -- named after the fact that it wakes people up during the night -- to more well-known pains in the head, like a monthly migraine.

Headaches are among the most common disorders of the nervous system, with almost half of the adult population experiencing a headache in 2015, according to the World Health Organization. They are started by an irritation of nerve fibers in the linings of the brain, causing pain, according to Dr. Patrick D. Lyden, chairman of the neurology department at Cedars-Sinai in the United States.

But the exact cause or trigger of many headaches is often hard to pinpoint, connected to such factors as diet, emotions, genes or hormones.

Here's a rundown of some of the most common, most painful and most disabling headaches people face today.

A new level of pain

Cluster headaches are considered by many experts to be the most painful type of headache a person could ever experience, affecting an estimated one in 1,000 people in the United States.

The headache targets one side of the head, with excruciating pain building in a matter of minutes, occasionally causing a stuffy or runny nose as well as redness and swelling of the eye.

The cause of an attack is unclear, but they can run in the family and are sometimes triggered by alcohol or strong smells such as perfume or petrol.

Justin Dolan, 30, of Belleville, New Jersey, has been living with cluster headaches for about 15 years. He said the headaches are unpredictable, come on rapidly and feel like the worst imaginable form of pain.

"It can only be described as a dull, hot knife digging into the back of your eye constantly. When my body is in a cluster headache cycle, these attacks affect my life, my relationships and my work," he said.

"There's severe stabbing, knife-like pain, which could last up to around three hours in duration," said Dr. Teshamae Monteith, assistant professor of clinical neurology at the University of Miami and member of the American Academy of Neurology. "They can happen multiple times during the day, often right before you go to bed and sometimes in the middle of the night, at around 4 a.m."

Many who experience cluster headaches believe they never truly understood pain until these episodes began, Monteith said. "The 0-10 scale that's often used to quantify pain has to be rewritten for cluster headache patients," she said.

Though some patients have them one to three times a year, some live with them for 11 months of the year, while others experience them for years on end, with little recovery time in between.

There's no cure for a cluster headache, and treatment is more complicated than a simple pill. In many cases, treatment involves breathing pure oxygen; injecting sumatriptan, a drug used to treat migraines; or inhaling a nasal form of local anesthetic to relieve symptoms.

There's also a recently FDA-approved noninvasive treatment called VNS -- vagus nerve stimulation -- that applies an electric current to the neck, activating the vagus nerve. The VNS device is about the size of a cell phone and is placed on the neck, with the aim to provide relief from pain. It's had some success in clinical trials, but more research on the procedure is needed, according to the US National Institutes for Health.

The two classes of migraine: More than just a headache

Migraines are by far the most common type of headache, according Cedars-Sinai's Lyden. Globally, 30% of people reported having a migraine in 2015, according to the WHO.

A classic migraine "is the one you've heard of. It's got the throbbing, pounding headache; it's got the lights in front of your eyes; it's got the nausea and vomiting," Lyden said.

The classic migraines might come with auras, which can affect language, movement and visual perception. Auras can occur separately from head pain but are triggered by the same factors that cause the pain of migraines, such as stress, bright lights or a lack of sleep.

"The most common presentation of migraine with aura is a visual disturbance. At times, patients can see flashing lights or stars in their visual field. They can see wiggly and wavy lines. There can be a hole in their visual field. There can be colors, spots in their visual field. This can last minutes to an hour (or more)," Monteith said.

"I've had patients that have been terrified of the visual loss, moreso than the actual head pain."

Monteith described how some migraines can mimic the symptoms of a stroke: The afflicted can go numb on one side of the body and/or lose the ability to speak coherently. But with regular migraine treatment such as prescription painkillers or another class of drugs known as triptan medications, they can be back to normal in hours.

Migraines without auras are far more common, with 70% to 90% of people with migraines experiencing this type. The main symptom here is a moderate or severe throbbing sensation that can worsen with movement and can prevent people from carrying out daily activities.

According to both Lyden and Monteith, the best way to treat migraines is to avoid having them in the first place. This means identifying triggers such as caffeine, poor sleep and lack of exercise. The last resort is medication, often anti-inflammatory medication such as aspirin or naproxen.

It's in the family

Whatever the migraine, it's highly likely you'll only experience them if you have a family history, because migraines are connected to your genes, according to Lyden.

"We're not sure what gene it is yet," Lyden said, adding that this genetic variation makes migraine patients more susceptible to pain in their head, but it also makes them more likely to suffer from motion sickness, nausea and vomiting, and vertigo.

"Their (gastrointestinal) tract is different, (and) their skin tends to react differently," he said, explaining that the genetic variation behind migraines also affects other parts of the body. As genes are an important tool for diagnosing migraines, Lyden said, he always makes sure to ask his patients for their family histories.

Decade-long pain

Migraines may come and go, but some headaches just won't go away.

A rare form of headache with the ability to last months or even years on end is known as new daily persistent headaches.

"(These) are a rare type of headache that happen one day and then persist. ... Patients with that headache can tell you the day and what they were doing when (it) started because it's so unusual," Monteith said. "It could persist for decades, or it could go away in three months or six months."

The exact cause of these headaches is unknown, but for some people, a very traumatic or emotional experience has marked the onset of the headache, Monteith said.

There's no specific treatment, and results vary from patient to patient, but some common pain medications such as amitriptyline, gabapentin and pregabalin have been shown to be effective in studies of adults and children. Daily painkillers are avoided, as they can result in medication-overuse headaches.

Medication-overuse headaches

This type is one of the most common chronic headache disorders, affecting 1% to 2% of people worldwide.

The headaches are caused by overusing acute pain relief medicine, such as paracetamol, codeine and triptans. They can be set off if people use the medicine more than two or three times a week or for more than 10 days a month.

When a dose of medicine wears off, the pain reappears, leading people to take more. Overuse then causes the medicine to stop helping the pain and start causing headaches instead.

The only way to stop medication-overuse headaches is to stop taking medication. This can be done either abruptly or gradually over time.

Bringing some relief

Headaches come in all shapes and sizes, from sharp, stabbing pain to prolonged dull aches.

To steer clear of the more average kinds, it's best to sleep well, avoid caffeine and get plenty of aerobic exercise. For any more unusual symptoms, make sure to see a doctor, who could help bring some much-needed relief.