INDIANAPOLIS — The Pacers took advantage of a depleted Philadelphia starting lineup for a 115-97 win in a Tuesday afternoon game at Bankers Life Fieldhouse.
The 76ers were playing without their leading scorer, Joel Embiid.
Indiana broke the game open in the second quarter, outscoring Philadelphia by 20 and leading by 24 at halftime.
The Pacers increased their lead to 30 heading into the final period.
Seven Indiana players scored in double figures, led by Domantas Sabonis with 23 points and 10 rebounds.
The 76ers, who are now 23-13, attempted 29 three-pointers making just six of them.
The Pacers are now 22-12 and host Denver Thursday.