INDIANAPOLIS — An Indiana University School of Medicine researcher is working with the Mayo Clinic on a study looking at blood biomarkers and Alzheimer’s disease.
Dr. Jeffrey Dage's previous studies have demonstrated that blood levels of phosphorylated tau (P-tau) are indicators of the development of Alzheimer’s disease pathology in the brain.
READ: Study from Dr. Dage and others
Blood-based biomarkers are the goal in screening for and diagnosing Alzheimer’s disease in the population because they are less costly and invasive than imaging and a lumbar puncture, Dage and Dr. Michelle Mielke with the Mayo Clinic said.
The IU School of Medicine says there are multiple ways for Hoosiers to get involved in the research, including donating blood to the Indiana Biobank or by completing a participant referral form.
Additionally, some Indiana patients will receive new screenings for early detection of Alzheimer’s disease thanks to a pilot program.
The program provides a digital cognitive assessment tool to screen patients for Alzheimer’s and electronically check brain function. Currently, those screenings are not part of normal primary care visits.
The Core Cognitive Evaluation is completely iPad-based and combines a digital assessment with a lifestyle-based patient questionnaire to generate actionable insights for both providers and patients.
-
IMPD safely finds missing 18-year-old
The eighteen-year-old was last seen on foot on Sunday, November 2, 2025, at approximately 9:15 a.m. in the 1000 block of N. Graham Avenue.
Three injured in downtown shooting
The Indianapolis Metropolitan Police Department is investigating a shooting in downtown that left three people injured early Sunday morning.
Thousands lose SNAP benefits as city launches emergency food effort
As thousands across Indianapolis face the sudden loss of food assistance, the city and its partners are launching emergency food distributions and funding to help families put food on the table.
Abandoned historic church's parish files petition to demolish building
St. Philip Neri Church, which merged with Holy Cross Church in 2014, filed a petition on Halloween for a judge to potentially overturn the building's status because of religious freedom.